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REPORTS /
MEMIOGRAPH
Survey and Cytogenetic
Study of Medicinal Plants of
Himachal Himalaya to Assess their Curative Value Against Genetic
Diseases, Savitri Verma, Department of Biosciences,
HPU, Shimla – 5
In the study, an attempt was made regarding
the anti-clastogenicity of seven medicinal plants extracts against
genotoxicity of potassium dichromate (K2Cr207) and Ethyl methanesulfonate
(EMS) in mice so as to assess their protective value against genetic
diseases. The plants selected for study were tea, turmeric, tulsi,
ginger, beri, amla and garlic. In case of study
regarding turmeric (Curcuma longa), tea (Camellia sinensis),
tulsi (Ocimum sanctum), ginger (Zingiber officinale),
berry (Ziziphus jujuba), amla (Phyllanthus emblica)
and garlic (Allium sativum), doses equivalent to or
less than recommended daily human consumption has been taken in
the present investigation. Also, in all cases crude aqueous extracts
were prepared in view of previous studies indicating better results
with such extracts. The results have shown that all the extracts
except that of ginger are able to reduce the clastogenic effects
of both K2Cr2O7 and EMS. So it
may be concluded that all the plants undertaken for present study,
except ginger, are able to minimize the genotoxicity of various
genotoxic agents such as K2Cr2O7
and EMS.
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