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Harnessing the Potential of the Microorganisms of Cold Desert of Himachal Pradesh for the Production of Enzymes of Therapeutic Importance, Wamik Azmi, Department of Biotechnology, HPU, Shimla

Over the past decades, the industrial use of microbial enzymes has developed rapidly because of their unique specificity for substrates, and is gathering increasing attention. However, in many cases, the substrates for the pharmaceutical development are artificial compounds, and enzyme to catalyze suitable reaction for such process is still unknown. Himachal Pradesh is endowed with unique and diverse microbial wealth. There are many microorganisms, particularly in upper reaches of the Himalayas, which have immense potential for use in the pharmaceutical industry. The full potential of those microorganisms for the production of therapeutic enzymes is still not assessed. The study was carried out with the objectives of collection of the soil and water samples from the cold desert of Himachal Pradesh; isolation of microbes from the soil and water samples; screening of the isolated microorganisms for the therapeutic enzymes; development of the method for the assay of the therapeutic enzymes and identification and characterization of microorganisms isolated from the cold desert area.

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